Journal article

Lifetime Body Mass Index Trajectories and Contrasting Lung Function Abnormalities in Mid-Adulthood: Data From the Tasmanian Longitudinal Health Study

GB Ali, AJ Lowe, EH Walters, JL Perret, B Erbas, CJ Lodge, G Bowatte, PS Thomas, GS Hamilton, BR Thompson, DP Johns, JL Hopper, MJ Abramson, DS Bui, SC Dharmage

Respirology | Published : 2025

DOI: 10.1111/resp.14882

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Abstract

Background and Objective: The impact of lifetime body mass index (BMI) trajectories on adult lung function abnormalities has not been investigated previously. We investigated associations of BMI trajectories from childhood to mid-adulthood with lung function deficits and COPD in mid-adulthood. Methods: Five BMI trajectories (n = 4194) from age 5 to 43 were identified in the Tasmanian Longitudinal Health Study. Lung function outcomes were defined using spirometry at 45 and 53 years. Associations between these BMI trajectories and lung function outcomes were investigated using multivariable regression. Results: Compared to the average BMI trajectory, the child's average-increasing BMI trajecto..

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Keywords

Restrictive‐lung Function
42 Health Sciences
Obstructive‐lung Function
Pediatric Research Initiative
Copd
Obesity Trajectories
Chronic Obstructive Pulmonary Disease
4206 Public Health
Poor Lung Function
Lifetime Growth Patterns
Women'S Health
Lifetime Obesity
Lung Function Decline
Respiratory
Body Mass Index Trajectories
Nutrition